Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | EPOR | P19235 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8650060 | 0.92 | TDP1 (0.41) | TDP1MEN1KMT2AEPORHTR2A | |
| SCHEMBL8525859 | 0.91 | TDP1 (0.40) | TDP1MEN1KMT2AEPORHTR2A | |
| SCHEMBL8126608 | 0.90 | TDP1 (0.41) | TDP1MEN1KMT2AEPORCNR1 | |
| SCHEMBL8127789 | 0.88 | TDP1 (0.46) | TDP1MEN1KMT2AHTTNPSR1 | |
| SCHEMBL8119409 | 0.86 | EPOR (0.43) | TDP1MEN1KMT2AEPORCNR1 | |
| SCHEMBL7750689 | 0.85 | MEN1 (0.42) | TDP1MEN1KMT2AHTTNPSR1 | |
| Hydrochloric Acid SCHEMBL8120628 | 0.84 | EPOR (0.41) | TDP1MEN1KMT2AEPORCNR1 | |
| SCHEMBL8651940 | 0.84 | EPOR (0.56) | EPOR | |
| SCHEMBL9196210 | 0.82 | TACR1 (0.36) | TDP1MEN1KMT2ANPSR1EPOR | |
| Hydrochloric Acid SCHEMBL8525856 | 0.82 | NPSR1 (0.41) | TDP1MEN1KMT2AHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865426-A1 | AMINO ACID DERIVATIVES, MEDICAMENTS CONTAINING SAID COMPOUNDS AND METHODS OF PRODUCING SAID COMPOUNDS | Dr. Karl Thomae GmbH (DE) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997019914-A1 | AMINO ACID DERIVATIVES, MEDICAMENTS CONTAINING SAID COMPOUNDS AND METHODS OF PRODUCING SAID COMPOUNDS | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |