Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL310117 | 0.89 | GPR119 (0.67) | GPR119HPGDRECQLEPHX1 | |
| SCHEMBL13274147 | 0.88 | GPR119 (0.65) | GPR119HPGDRECQLEPHX1 | |
| SCHEMBL21359212 | 0.84 | EPHX1 (0.62) | GPR119HPGDRECQLEPHX1 | |
| SCHEMBL19702701 | 0.83 | EPHX1 (0.65) | GPR119HPGDRECQLEPHX1 | |
| SCHEMBL5567218 | 0.83 | GPR119 (0.60) | GPR119HPGDRECQLEPHX1 | |
| SCHEMBL8661760 | 0.83 | GPR119 (0.64) | GPR119HPGDRECQLEPHX1 | |
| SCHEMBL12440604 | 0.83 | GPR119 (0.60) | GPR119HPGDRECQLEPHX1 | |
| SCHEMBL31551882 | 0.82 | GPR119 (0.59) | GPR119HPGDRECQLEPHX1PTPN2 | |
| SCHEMBL653566 | 0.82 | USP2 (0.58) | GPR119HPGDRECQLEPHX1 | |
| SCHEMBL2674022 | 0.81 | RECQL (0.59) | GPR119HPGDRECQLEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0964928-A1 | ENZYMATIC RESOLUTION OF BENZODIAZEPINE-ACETIC ACID ESTERS WITH A LIPASE | SMITHKLINE BEECHAM PLC (GB) | 1999-12-22 | — | — | EP | claimed |
| WO-1998029561-A1 | ENZYMATIC RESOLUTION OF BENZODIAZEPINE-ACETIC ACID ESTERS WITH A LIPASE | SMITHKLINE BEECHAM PLC (GB) | 1998-07-09 | — | — | WO | claimed |
| EP-0964928-A1 | ENZYMATIC RESOLUTION OF BENZODIAZEPINE-ACETIC ACID ESTERS WITH A LIPASE | SMITHKLINE BEECHAM PLC (GB) | 1999-12-22 | — | — | EP | disclosed |
| WO-1998029561-A1 | ENZYMATIC RESOLUTION OF BENZODIAZEPINE-ACETIC ACID ESTERS WITH A LIPASE | SMITHKLINE BEECHAM PLC (GB) | 1998-07-09 | — | — | WO | disclosed |