⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL551176 | 0.97 | — | — | |
| SCHEMBL551175 | 0.97 | — | — | |
| SCHEMBL239631 | 0.92 | — | — | |
| SCHEMBL5606894 | 0.79 | — | — | |
| SCHEMBL11287030 | 0.78 | ALDH1A1 (0.31) | — | |
| SCHEMBL11287028 | 0.78 | ALDH1A1 (0.31) | — | |
| SCHEMBL11288135 | 0.72 | — | — | |
| SCHEMBL17871004 | 0.71 | — | — | |
| SCHEMBL711453 | 0.71 | — | — | |
| SCHEMBL1232859 | 0.71 | KDM4E (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113816818-B | Copper-catalyzed asymmetric allylic alkylation reaction method and chiral compound | 哈尔滨工业大学（深圳） | 2023-07-25 | — | — | CN | claimed |
| CN-114149421-A | Palmatine derivative, preparation method and antithrombotic application thereof | 中国医学科学院医药生物技术研究所 | 2022-03-08 | — | — | CN | claimed |
| CN-113816818-B | Copper-catalyzed asymmetric allylic alkylation reaction method and chiral compound | 哈尔滨工业大学（深圳） | 2023-07-25 | — | — | CN | disclosed |
| CN-114149421-B | Palmatine derivatives, preparation method and antithrombotic use thereof | 中国医学科学院医药生物技术研究所 | 2023-04-25 | — | — | CN | disclosed |
| CN-114149421-A | Palmatine derivative, preparation method and antithrombotic application thereof | 中国医学科学院医药生物技术研究所 | 2022-03-08 | — | — | CN | disclosed |
| CN-113816818-A | Copper-catalyzed asymmetric allyl alkylation reaction method and chiral compound | 哈尔滨工业大学（深圳） | 2021-12-21 | — | — | CN | disclosed |
| EP-3564240-A1 | PIPERIDINE INTERMEDIATES | Purdue Pharma L.P. (US) | 2019-11-06 | — | — | EP | disclosed |
| US-9527840-B2 | Substituted-quinoxaline-type piperidine compounds and the uses thereof | PURDUE PHARMA L.P. (US) | 2016-12-27 | — | — | US | disclosed |
| US-9527840-B2 | Substituted-quinoxaline-type piperidine compounds and the uses thereof | PURDUE PHARMA L.P. (US) | 2016-12-27 | — | — | US | disclosed |
| US-9527840-B2 | Substituted-quinoxaline-type piperidine compounds and the uses thereof | PURDUE PHARMA L.P. (US) | 2016-12-27 | — | — | US | disclosed |
| EP-3101018-A1 | SUBSTITUTED-QUINOXALINE-TYPE-PIPERIDINE COMPOUNDS AND THE USES THEREOF | Purdue Pharma L.P. (US) | 2016-12-07 | — | — | EP | disclosed |
| EP-0128006-A2 | A soil-disease-controlling agent | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-12-12 | — | — | EP | disclosed |
| EP-0000555-B1 | PROCESS FOR THE PREPARATION OF OXIRANES SUBSTITUTED BY HALOGEN ALKYL | BAYER AG (DE) | 1982-02-10 | — | — | EP | disclosed |
| US-4228295-A | Novel cycloheptathiophene intermediates for the synthesis of biotin | HOFFMANN-LA ROCHE INC. (US) | 1980-10-14 | — | — | US | disclosed |
| US-4228168-A | ANTI-ANOXIC ACTIVITY | TANABE SEIYAKU CO., LTD. (JP) | 1980-10-14 | — | — | US | disclosed |
| US-4175086-A | Cycloheptathiophene derivatives | HOFFMANN-LA ROCHE INC. (US) | 1979-11-20 | — | — | US | disclosed |
| EP-0000554-A1 | Process for the preparation of oxiranes substituted by halogen alkyl | BAYER AG (DE) | 1979-02-07 | — | — | EP | disclosed |
| US-4124595-A | Synthesis of biotin | HOFFMANN-LA ROCHE INC. (US) | 1978-11-07 | — | — | US | disclosed |
| US-4062868-A | Synthesis of biotin | HOFFMANN-LA ROCHE INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-4017539-A | Biguanide compounds and anti-diabetic compositions | BOEHRINGER MANNHEIM G.M.B.H. (DT) | 1977-04-12 | — | — | US | disclosed |