Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | MLNR | O43193 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrabuthylammonium SCHEMBL3258305 | 0.87 | CA12 (0.43) | CA12CA9PTPN1ALDH1A1LMNA | |
| Saccharin SCHEMBL5679534 | 0.81 | CYP3A4 (0.37) | CA12CA9MEN1KMT2AALDH1A1 | |
| Saccharin SCHEMBL196947 | 0.76 | CA12 (0.59) | CA12CA9DNM1APAF1HSP90AA1 | |
| Cetrimonium SCHEMBL196676 | 0.76 | CA12 (0.59) | CA12CA9DNM1APAF1HSP90AA1 | |
| Saccharin SCHEMBL473608 | 0.75 | GPR3 (0.44) | CA12CA9MEN1KMT2AALDH1A1 | |
| Saccharin SCHEMBL10618576 | 0.75 | GPR3 (0.44) | CA12CA9MEN1KMT2AALDH1A1 | |
| Saccharin SCHEMBL10399957 | 0.75 | GPR3 (0.44) | CA12CA9MEN1KMT2AALDH1A1 | |
| Saccharin SCHEMBL787894 | 0.75 | GPR3 (0.44) | CA12CA9MEN1KMT2AALDH1A1 | |
| Saccharin SCHEMBL5870938 | 0.75 | GPR3 (0.44) | CA12CA9MEN1KMT2AALDH1A1 | |
| Saccharin SCHEMBL8668442 | 0.75 | GPR3 (0.44) | CA12CA9MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0897427-A1 | POLYSACCHARIDE PRECIPITATION PROCESS | Merck & Co., Inc. (US) | 1999-02-24 | — | — | EP | claimed |
| WO-1997030171-A1 | POLYSACCHARIDE PRECIPITATION PROCESS | MERCK & CO., INC. (US) | 1997-08-21 | — | — | WO | claimed |