SCHEMBL8526170

SCHEMBL8526170

C=CC(=O)OC#COOC(C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9576253 0.78 TSHR (0.40) TSHR
SCHEMBL8526431 0.76 TSHR (0.46) TSHR
SCHEMBL8526037 0.76 MAPK1 (0.44) TSHR
SCHEMBL15300605 0.73 ALDH1A1 (0.37) TSHR
SCHEMBL9718351 0.71 TSHR (0.50) TSHR
SCHEMBL8881160 0.70 TSHR (0.38) TSHR
SCHEMBL3789568 0.70
Chloromethane SCHEMBL28170022 0.68 TSHR (0.38) TSHR
SCHEMBL4138048 0.65 TSHR (0.35) TSHR
SCHEMBL30658 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0906937-A1 Graft copolymer obtained by free-radical polymerisation with stable free-radicals, its preparation and uses ELF ATOCHEM S.A. (FR) 1999-04-07 EP disclosed