SCHEMBL8526308

CCOC(=O)NC(=O)NCc1ccc(CN([C@@H](CCCNC(=N)N)C(=O)NC(=O)C(c2ccccc2)c2ccccc2)S(=O)(=O)c2c(C)c(C)c3c(c2C)CCC(C)(C)O3)cc1

nearest known ligand 0.35

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	NPY1R	P25929	7/20	0.35

▸	PLG	P00747	2/20	0.35

▸	F10	P00742	1/20	0.35

▸	PLAU	P00749	1/20	0.35

▸	KLKB1	P03952	1/20	0.35

▸	NPFFR1	Q9GZQ6	1/20	0.33

▸	BMP1	P13497	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8609799	0.88	PLG (0.35)	PLGF10PLAUKLKB1
SCHEMBL8526348	0.82	PLG (0.40)	PLGF10PLAUKLKB1
SCHEMBL8584082	0.79	PLG (0.38)	NPY1RPLGF10PLAUKLKB1
SCHEMBL8587026	0.78	PLG (0.34)	NPY1RPLGF10PLAUKLKB1
SCHEMBL8526791	0.77	PLG (0.39)	PLGF10PLAUKLKB1
SCHEMBL8525681	0.77	PLG (0.40)	NPY1RPLGF10PLAUKLKB1
SCHEMBL8528243	0.75	PLG (0.36)	PLGF10PLAUKLKB1
SCHEMBL8526347	0.74	PLG (0.40)	NPY1RPLGF10PLAUKLKB1
SCHEMBL8582403	0.74	PLG (0.37)	PLGF10PLAUKLKB1
SCHEMBL8525928	0.74	PLG (0.39)	NPY1RPLGF10PLAUKLKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0885186-A1	AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM	Dr. Karl Thomae GmbH (DE)	1998-12-23	—	—	EP	disclosed
WO-1997019911-A1	AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM	DR. KARL THOMAE GMBH (DE)	1997-06-05	—	—	WO	disclosed