Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 3/20 | 0.40 |
| ▸ | PLAU | P00749 | 2/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | NPY4R | P50391 | 7/20 | 0.33 |
| ▸ | NPY1R | P25929 | 5/20 | 0.33 |
| ▸ | NPY2R | P49146 | 4/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.32 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 7/20 | 0.30 |
| ▸ | ACHE | P22303 | 7/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8526348 | 0.88 | PLG (0.40) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL8526287 | 0.82 | PLG (0.48) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL8525681 | 0.80 | PLG (0.40) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL7170054 | 0.79 | PLG (0.35) | PLGPLAUF10KLKB1NPY4R | |
| SCHEMBL7170382 | 0.79 | PLG (0.35) | PLGPLAUF10KLKB1NPY4R | |
| SCHEMBL8525928 | 0.78 | PLG (0.39) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL7165122 | 0.78 | PLG (0.35) | PLGPLAUF10KLKB1 | |
| SCHEMBL7038734 | 0.78 | PLG (0.47) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL7744390 | 0.77 | PLG (0.40) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL8584082 | 0.77 | PLG (0.38) | PLGPLAUF10KLKB1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |