Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.44 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL109296 | 0.85 | PLA2G2C (0.45) | MAPTGPR84FFAR1LCKPPARD | |
| SCHEMBL15283647 | 0.84 | GPR84 (0.44) | MAPTGPR84FFAR1LCKPPARD | |
| SCHEMBL18425829 | 0.81 | MAPT (0.41) | MAPTGPR84FFAR1LCKPPARD | |
| SCHEMBL8597199 | 0.79 | SPHK1 (0.38) | MAPTGPR84FFAR1LCKPPARD | |
| SCHEMBL1649294 | 0.77 | PLA2G2C (0.44) | PLA2G2C | |
| SCHEMBL4323327 | 0.77 | PLA2G2C (0.44) | PLA2G2C | |
| SCHEMBL10384273 | 0.76 | SPHK1 (0.35) | MAPTGPR84FFAR1ZDHHC7 | |
| SCHEMBL5012513 | 0.76 | PLA2G2C (0.56) | MAPTGPR84FFAR1LCKPPARD | |
| SCHEMBL20459159 | 0.76 | PLA2G2C (0.56) | MAPTGPR84FFAR1LCKPPARD | |
| SCHEMBL9853678 | 0.76 | MAPT (0.41) | MAPTGPR84FFAR1LCKPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998368-A | Derivatives of structurally modified VIP and pharmaceutical compositions containing them | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 1999-12-07 | — | — | US | disclosed |