Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8525033 | 0.92 | LRRK2 (0.35) | MAPK10HSD11B1LRRK2MMP12CTSS | |
| SCHEMBL8524723 | 0.86 | MAPK10 (0.35) | MAPK10HSD11B1LRRK2P2RX7MMP12 | |
| SCHEMBL8524806 | 0.84 | MAPK10 (0.39) | MAPK10HSD11B1LRRK2MAPTALDH1A1 | |
| SCHEMBL8525613 | 0.83 | MAPK10 (0.40) | MAPK10LRRK2MAPTHSP90AA1HTT | |
| SCHEMBL8524928 | 0.83 | LRRK2 (0.39) | MAPK10HSD11B1LRRK2CTSSMAPT | |
| SCHEMBL8525911 | 0.81 | LRRK2 (0.38) | MAPK10HSD11B1LRRK2CTSSMAPT | |
| SCHEMBL8524688 | 0.79 | LRRK2 (0.39) | MAPK10HSD11B1LRRK2CTSSMAPT | |
| SCHEMBL8525003 | 0.79 | LRRK2 (0.40) | MAPK10HSD11B1LRRK2MAPTALDH1A1 | |
| SCHEMBL8180740 | 0.73 | MAPK10 (0.43) | MAPK10LRRK2CTSSMAPTALDH1A1 | |
| SCHEMBL8525061 | 0.72 | F9 (0.37) | MMP12MAPTALDH1A1HSP90AA1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999003856-A1 | 4-BENZOYL-ISOXAZOLE- AND -PYRAZOLE DERIVATIVES AND 2-CYANO 1,3-DIONE DERIVATIVES AS HERBICIDES | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-28 | — | — | WO | disclosed |