Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RXRA | P19793 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8525843 | 0.86 | PTGER1 (0.39) | MAPK10PTGER1LRRK2SMN1; SMN2NPC1 | |
| SCHEMBL8524806 | 0.85 | MAPK10 (0.39) | MAPK10LRRK2SMN1; SMN2MAPTHSP90AA1 | |
| SCHEMBL8525003 | 0.85 | LRRK2 (0.40) | MAPK10LRRK2SMN1; SMN2RAB9AMAPT | |
| SCHEMBL8526508 | 0.83 | MAPK10 (0.38) | MAPK10LRRK2SMN1; SMN2MAPTHSP90AA1 | |
| SCHEMBL8524928 | 0.83 | LRRK2 (0.39) | MAPK10LRRK2SMN1; SMN2RAB9AMAPT | |
| SCHEMBL8525911 | 0.82 | LRRK2 (0.38) | MAPK10LRRK2SMN1; SMN2MAPTHSP90AA1 | |
| SCHEMBL8524688 | 0.80 | LRRK2 (0.39) | MAPK10LRRK2SMN1; SMN2RAB9AMAPT | |
| SCHEMBL8525033 | 0.78 | LRRK2 (0.35) | MAPK10LRRK2SMN1; SMN2MAPTHSP90AA1 | |
| SCHEMBL8525951 | 0.75 | MAPT (0.41) | MAPK10LRRK2SMN1; SMN2MAPTHSP90AA1 | |
| SCHEMBL8180740 | 0.74 | MAPK10 (0.43) | MAPK10LRRK2SMN1; SMN2RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999003856-A1 | 4-BENZOYL-ISOXAZOLE- AND -PYRAZOLE DERIVATIVES AND 2-CYANO 1,3-DIONE DERIVATIVES AS HERBICIDES | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-28 | — | — | WO | disclosed |