SCHEMBL8526613

SCHEMBL8526613

CC(C)CC(Cl)C(=O)C(Cl)CC(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RNPEP Q9H4A4 1/20 0.40
SLC7A5 Q01650 1/20 0.40
ALDH1A1 P00352 3/20 0.35
TDP1 Q9NUW8 1/20 0.35
CACNA2D1 P54289 2/20 0.34
CACNB3 P54284 1/20 0.34
CACNA1C Q13936 1/20 0.34
PGR P06401 1/20 0.34
ADRA1A P35348 1/20 0.34
HTR2B P41595 1/20 0.34
CACNA2D2 Q9NY47 1/20 0.34
SLC1A3 P43003 1/20 0.34
SLC1A2 P43004 1/20 0.34
ANPEP P15144 3/20 0.33
LAP3 P28838 2/20 0.33
ERAP1 Q9NZ08 1/20 0.33
CPA1 P15085 2/20 0.32
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL50414 0.82
SCHEMBL4968926 0.80
SCHEMBL936160 0.80
SCHEMBL4971280 0.80
SCHEMBL4968921 0.80
SCHEMBL1066841 0.80
SCHEMBL4460826 0.76 RNPEP (0.36) RNPEPSLC7A5ALDH1A1TDP1CACNA2D1
SCHEMBL25158974 0.74 MME (0.41)
SCHEMBL11435031 0.74 MME (0.41)
SCHEMBL16215927 0.74 MME (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5992354-A Combustion of nanopartitioned fuel MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1999-11-30 US disclosed