SCHEMBL1066841

SCHEMBL1066841

CC(=O)C(Cl)CC(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6760286 0.85 ALDH1A1 (0.32)
SCHEMBL8931332 0.83
SCHEMBL50414 0.80
SCHEMBL8526613 0.80 RNPEP (0.40)
SCHEMBL936160 0.78
SCHEMBL4971280 0.78
SCHEMBL4968921 0.78
SCHEMBL25656353 0.78
SCHEMBL4968926 0.78
SCHEMBL11465685 0.74 ALDH1A1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0952140-B1 2-Hydroxy-5-methyl-hexan-3-one and 3-hydroxy-5-methyl-hexan-2-one GIVAUDAN SA (CH) 2004-04-28 EP claimed
US-6426108-B1 CHLORINATION KETONE USING SULFURYL CHLORIDE; ESTERIFICATION; HYDROLYSIS GIVAUDAN SA (CH) 2002-07-30 US claimed
EP-0952140-A1 Hydroxy-methyl-hexanones Givaudan Roure (International) S.A. (CH) 1999-10-27 EP claimed
EP-3215505-B1 PIPERIDINYLPYRAZOLOPYRIMIDINONES AND THEIR USE Bayer Pharma AG (DE) 2019-07-24 EP disclosed
US-10118930-B2 Piperidinylpyrazolopyrimidinones and their use BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2018-11-06 US disclosed
US-20170334917-A1 PIPERIDINYLPYRAZOLOPYRIMIDINONES AND THEIR USE BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2017-11-23 US disclosed
EP-3215505-A1 PIPERIDINYLPYRAZOLOPYRIMIDINONES AND THEIR USE Bayer Pharma Aktiengesellschaft (DE) 2017-09-13 EP disclosed
WO-2016071216-A1 PIPERIDINYLPYRAZOLOPYRIMIDINONES AND THEIR USE BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2016-05-12 WO disclosed
US-9169282-B2 Metal complexes MERCK PATENT GMBH (DE) 2015-10-27 US disclosed
US-9169282-B2 Metal complexes MERCK PATENT GMBH (DE) 2015-10-27 US disclosed
US-8987256-B2 Oxo-heterocyclic substituted carboxylic acid derivatives and the use thereof BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-03-24 US disclosed
WO-2010086089-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2010-08-05 WO disclosed
WO-2009127338-A1 OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATES AND THE USE THEREOF BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2009-10-22 WO disclosed
EP-0952140-B1 2-Hydroxy-5-methyl-hexan-3-one and 3-hydroxy-5-methyl-hexan-2-one GIVAUDAN SA (CH) 2004-04-28 EP disclosed
US-6426108-B1 CHLORINATION KETONE USING SULFURYL CHLORIDE; ESTERIFICATION; HYDROLYSIS GIVAUDAN SA (CH) 2002-07-30 US disclosed
US-6123974-A 2-HYDROXY-5-METHYL-HEXAN-3-ONE AND MIXTURES WITH 3-HYDROXY-5-METHYL-HEXAN-2-ONE; USE AS FLAVORING AND MASKING AGENTS SUCH AS FOR SOYBEAN-BASED FOOD AND BEVERAGES GIVAUDAN ROURE (INTERNATIONAL) SA (CH) 2000-09-26 US disclosed
JP-2000053607-A HYDROXY-METHYL-HEXANONE GIVAUDAN ROURE INTERNATL SA 2000-02-22 JP disclosed
CN-1235150-A Hydroxy-methyl-hexanones GIVAUDAN ROURE INT (CH) 1999-11-17 CN disclosed
EP-0952140-A1 Hydroxy-methyl-hexanones Givaudan Roure (International) S.A. (CH) 1999-10-27 EP disclosed
US-4240983-A HALOGENATION BAYER AKTIENGESELLSCHAFT (DE) 1980-12-23 US disclosed