Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.54 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4411502 | 0.76 | CNR2 (0.63) | CNR2CNR1MAPTKDM4EPOLB | |
| SCHEMBL4415634 | 0.76 | CNR2 (0.81) | CNR2CNR1ALDH1A1KDM4E | |
| SCHEMBL4408455 | 0.72 | CNR2 (0.63) | CNR2CNR1MAPTKDM4EPOLB | |
| SCHEMBL4409113 | 0.72 | CNR2 (0.55) | CNR2CNR1KDM4EPOLB | |
| Hydrochloric Acid SCHEMBL8085888 | 0.71 | CNR2 (0.54) | CNR2CNR1KDM4EPOLB | |
| SCHEMBL4406833 | 0.70 | CNR2 (0.49) | CNR2CNR1MAPTKDM4EPOLB | |
| SCHEMBL4414324 | 0.70 | CNR2 (0.49) | CNR2CNR1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL4408457 | 0.70 | CNR2 (1.00) | CNR2LMNA | |
| SCHEMBL4408203 | 0.70 | CNR2 (0.76) | CNR2ALDH1A1TP53 | |
| SCHEMBL8089408 | 0.69 | CNR2 (0.65) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0887340-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL USE THEREOF | Japan Tobacco Inc. (JP) | 1998-12-30 | — | — | EP | claimed |