SCHEMBL8089408

SCHEMBL8089408

CCCCCOc1c(OC)ccc2c(=O)n(CCc3ccc(O)cc3)sc12

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 15/20 0.65
CNR1 P21554 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4408457 0.79 CNR2 (1.00) CNR2
SCHEMBL4411502 0.77 CNR2 (0.63) CNR2CNR1
SCHEMBL8091179 0.73 CNR2 (1.00) CNR2
SCHEMBL4416320 0.72 CNR2 (0.88) CNR2
SCHEMBL4405983 0.72 CNR2 (1.00) CNR2CNR1
SCHEMBL4409616 0.71 CNR2 (1.00) CNR2
SCHEMBL4415364 0.69 CNR2 (0.83) CNR2
SCHEMBL8526705 0.69 CNR2 (0.54) CNR2CNR1
SCHEMBL8085623 0.69 CNR2 (0.71) CNR2CNR1
SCHEMBL4407773 0.69 CNR2 (0.81) CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6017919-A Compounds and pharmaceutical use thereof JAPAN TOBACCO INC. (JP) 2000-01-25 US disclosed
EP-0887340-A1 NOVEL COMPOUNDS AND PHARMACEUTICAL USE THEREOF Japan Tobacco Inc. (JP) 1998-12-30 EP disclosed