SCHEMBL8526771

SCHEMBL8526771

O=C(O)COCC(COC(=O)OCC1c2ccccc2-c2ccccc21)OC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.43
FABP5 Q01469 3/20 0.43
FABP7 O15540 2/20 0.43
CASP3 P42574 2/20 0.40
EPHX2 P34913 1/20 0.39
TLR2 O60603 3/20 0.37
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
MDM4 O15151 1/20 0.36
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29503802 0.81 FABP5 (0.52) KMT2AFABP5FABP7CASP3EPHX2
SCHEMBL10263237 0.81 FABP5 (0.52) KMT2AFABP5FABP7CASP3EPHX2
SCHEMBL44676 0.78 KMT2A (0.58) KMT2AFABP5FABP7CASP3EPHX2
SCHEMBL13981720 0.75 KMT2A (0.47) KMT2AFABP5FABP7CASP3EPHX2
SCHEMBL10201861 0.74 KMT2A (0.49) KMT2AFABP5FABP7CASP3EPHX2
SCHEMBL9117229 0.74 CASP3 (0.50) KMT2AFABP5FABP7CASP3EPHX2
SCHEMBL17669877 0.74 CASP3 (0.50) KMT2ACASP3TLR2MDM4TP53
SCHEMBL17669878 0.74 CASP3 (0.50) KMT2ACASP3TLR2MDM4TP53
SCHEMBL9116636 0.73 CASP3 (0.47) KMT2AFABP5FABP7CASP3EPHX2
SCHEMBL21436038 0.73 KMT2A (0.43) KMT2AFABP5FABP7CASP3EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0885236-A1 OLIGONUCLEOTIDE ANALOGS Codon Pharmaceuticals, Inc. (US) 1998-12-23 EP disclosed
WO-1997027206-A1 OLIGONUCLEOTIDE ANALOGS CODON PHARMACEUTICALS, INC. (US) 1997-07-31 WO disclosed