Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 4/20 | 0.41 |
| ▸ | MMP8 | P22894 | 4/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | AVPR1B | P47901 | 4/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 6/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28516145 | 0.77 | AVPR1B (0.45) | BMP1MMP8AVPR1BAVPR1APLG | |
| SCHEMBL28516147 | 0.77 | AVPR1B (0.45) | BMP1MMP8AVPR1BAVPR1APLG | |
| SCHEMBL8526348 | 0.77 | PLG (0.40) | PLGF2 | |
| SCHEMBL28860154 | 0.74 | AVPR1B (0.39) | BMP1MMP8MMP1AVPR1BAVPR1A | |
| SCHEMBL28860152 | 0.74 | AVPR1B (0.39) | BMP1MMP8MMP1AVPR1BAVPR1A | |
| SCHEMBL9329697 | 0.73 | AVPR1B (0.52) | BMP1AVPR1BAVPR1APLGF2 | |
| SCHEMBL28514278 | 0.71 | AVPR1B (0.39) | BMP1MMP8MMP1AVPR1BAVPR1A | |
| SCHEMBL7898282 | 0.71 | AVPR1B (0.54) | BMP1AVPR1BAVPR1APLGF2 | |
| SCHEMBL1509780 | 0.71 | AVPR1B (0.54) | BMP1AVPR1BAVPR1APLGF2 | |
| SCHEMBL1509781 | 0.71 | AVPR1B (0.54) | BMP1AVPR1BAVPR1APLGF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |