Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | CDK9 | P50750 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2311252 | 1.00 | SPHK1 (0.55) | SPHK1POLBMEN1ALDH1A1MAPT | |
| SCHEMBL8526956 | 1.00 | SPHK1 (0.55) | SPHK1POLBMEN1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL20569864 | 0.98 | SPHK1 (0.54) | SPHK1POLBMEN1ALDH1A1MAPT | |
| SCHEMBL8607633 | 0.87 | KMT2A (0.46) | SPHK1POLBMEN1ALDH1A1MAPT | |
| SCHEMBL29410403 | 0.85 | POLB (0.53) | POLBMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL10791327 | 0.83 | MEN1 (0.60) | POLBMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL5072176 | 0.83 | MME (0.53) | POLBMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL14209990 | 0.83 | MEN1 (0.60) | POLBMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL5270163 | 0.83 | MEN1 (0.60) | POLBMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL3954076 | 0.83 | LTA4H (0.67) | POLBMEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383778-B1 | AGONISTS AND ANTAGONISTS OF SPHINGOSINE-1-PHOSPHATE RECEPTORS | UNIV VIRGINIA (US) | 2009-10-21 | — | — | EP | disclosed |
| US-5773284-A | REACTING GLYCINE AMIDE WITH BENZALDEHYDE | DSM N.V. (NL) | 1998-06-30 | — | — | US | disclosed |
| US-5773284-A | REACTING GLYCINE AMIDE WITH BENZALDEHYDE | DSM N.V. (NL) | 1998-06-30 | — | — | US | disclosed |
| EP-0734453-A1 | PHENYLSERINE AMIDES AND THE PREPARATION OF PHENYLSERINES/PHENYLSERINE AMIDES | DSM N.V. (NL) | 1996-10-02 | — | — | EP | disclosed |
| EP-0734453-A1 | PHENYLSERINE AMIDES AND THE PREPARATION OF PHENYLSERINES/PHENYLSERINE AMIDES | DSM N.V. (NL) | 1996-10-02 | — | — | EP | disclosed |
| WO-1995016786-A1 | PHENYLSERINE AMIDES AND THE PREPARATION OF PHENYLSERINES/PHENYLSERINE AMIDES | DSM N.V. (NL) | 1995-06-22 | — | — | WO | disclosed |
| WO-1995016786-A1 | PHENYLSERINE AMIDES AND THE PREPARATION OF PHENYLSERINES/PHENYLSERINE AMIDES | DSM N.V. (NL) | 1995-06-22 | — | — | WO | disclosed |