Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.55 |
| ▸ | F7 | P08709 | 4/20 | 0.55 |
| ▸ | F3 | P13726 | 4/20 | 0.55 |
| ▸ | PPARG | P37231 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | OXER1 | Q8TDS5 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.55 |
| ▸ | PPARD | Q03181 | 3/20 | 0.55 |
| ▸ | PPARA | Q07869 | 3/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13491390 | 0.98 | ALDH1A1 (0.52) | ALDH1A1CYP19A1F7F3PPARG | |
| SCHEMBL29813121 | 0.92 | ALDH1A1 (0.42) | ALDH1A1CYP19A1F7F3PPARG | |
| SCHEMBL2328163 | 0.88 | ALDH1A1 (0.55) | ALDH1A1CYP19A1F7F3PPARG | |
| SCHEMBL17744175 | 0.88 | ALDH1A1 (0.55) | ALDH1A1CYP19A1F7F3PPARG | |
| SCHEMBL1994402 | 0.88 | ALDH1A1 (0.55) | ALDH1A1CYP19A1F7F3PPARG | |
| SCHEMBL17744173 | 0.88 | ALDH1A1 (0.55) | ALDH1A1CYP19A1F7F3PPARG | |
| SCHEMBL18708267 | 0.88 | ALDH1A1 (0.55) | ALDH1A1CYP19A1F7F3PPARG | |
| SCHEMBL18923149 | 0.88 | ALDH1A1 (0.50) | ALDH1A1CYP19A1F7F3PPARG | |
| SCHEMBL16968356 | 0.85 | ALDH1A1 (0.42) | ALDH1A1CYP19A1F7F3PPARG | |
| SCHEMBL23704055 | 0.83 | FFAR1 (0.53) | ALDH1A1CYP19A1F7F3PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0827401-A2 | METHODS AND COMPOSITIONS FOR INHIBITING ALPHA-REDUCTASE ACTIVITY | ARCH DEVELOPMENT CORPORATION (US) | 1998-03-11 | — | — | EP | disclosed |
| WO-1996037201-A2 | METHODS AND COMPOSITIONS FOR INHIBITING 5α-REDUCTASE ACTIVITY | ARCH DEVELOPMENT CORPORATION (US) | 1996-11-28 | — | — | WO | disclosed |