Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 6/20 | 0.64 |
| ▸ | PPIB | P23284 | 1/20 | 0.64 |
| ▸ | PPIA | P62937 | 1/20 | 0.64 |
| ▸ | PPIG | Q13427 | 1/20 | 0.64 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 4/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8527136 | 0.83 | PPID (0.62) | PPIDPPIBPPIAPPIGEPHX1 | |
| SCHEMBL2037313 | 0.79 | PPID (0.75) | PPIDPPIBPPIAPPIGLMNA | |
| SCHEMBL15832153 | 0.79 | NPC1 (0.60) | PPIDPPIBPPIAPPIGLMNA | |
| SCHEMBL2044119 | 0.79 | PPID (1.00) | PPIDPPIBPPIAPPIGEPHX1 | |
| SCHEMBL14617663 | 0.78 | PPID (0.78) | PPIDPPIBPPIAPPIGLMNA | |
| SCHEMBL2034584 | 0.77 | PPID (0.57) | PPIDPPIBPPIAPPIGGLA | |
| Hydrochloric Acid SCHEMBL8136996 | 0.77 | PPID (0.77) | PPIDPPIBPPIAPPIGHTT | |
| SCHEMBL2034522 | 0.77 | PPID (0.76) | PPIDPPIBPPIAPPIGLMNA | |
| SCHEMBL177524 | 0.77 | PPID (0.67) | PPIDPPIBPPIAPPIG | |
| SCHEMBL12643634 | 0.76 | PPID (0.74) | PPIDPPIBPPIAPPIGLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |