Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.55 |
| ▸ | MEN1 | O00255 | 7/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | IDE | P14735 | 1/20 | 0.51 |
| ▸ | MPI | P34949 | 1/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.51 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | KDM5A | P29375 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11282853 | 0.92 | KDM4E (0.52) | KMT2AMEN1PGRKDM4ESMN1; SMN2 | |
| SCHEMBL9182411 | 0.92 | KDM4E (0.52) | KMT2AMEN1PGRKDM4ESMN1; SMN2 | |
| SCHEMBL11983217 | 0.90 | KDM4E (0.50) | KMT2AMEN1KDM4ESMN1; SMN2NLRP3 | |
| SCHEMBL11291469 | 0.90 | KMT2A (0.50) | KMT2AMEN1PGRKDM4ESMN1; SMN2 | |
| SCHEMBL11285148 | 0.89 | KDM4E (0.50) | KMT2AMEN1PGRKDM4ESMN1; SMN2 | |
| SCHEMBL9185831 | 0.88 | MEN1 (0.49) | KMT2AMEN1PGRKDM4EALDH1A1 | |
| SCHEMBL11983191 | 0.87 | KDM4E (0.51) | KMT2AMEN1PGRKDM4ESMN1; SMN2 | |
| SCHEMBL11983188 | 0.87 | KDM4E (0.48) | KMT2AMEN1PGRKDM4ESMN1; SMN2 | |
| SCHEMBL9186522 | 0.87 | KDM4E (0.51) | KMT2AMEN1KDM4ESMN1; SMN2NLRP3 | |
| SCHEMBL9182334 | 0.87 | KMT2A (0.48) | KMT2AMEN1PGRKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376456-A2 | HIGHLY PURE LAQUINIMOD OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Actavis Group Ptc Ehf (IS) | 2011-10-19 | — | — | EP | claimed |
| WO-2010070449-A2 | HIGHLY PURE LAQUINIMOD OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ACTAVIS GROUP PTC EHF (IS) | 2010-06-24 | — | — | WO | claimed |
| EP-0429627-B1 | DERIVATIVES OF QUINOLINE-3-CARBOXANILIDE | PHARMACIA AB REG NUMBER 556131 (SE) | 1995-09-13 | — | — | EP | claimed |
| US-5310913-A | Immunomodulators | KABI PHARMACIA AKTIEBOLAG (SE) | 1994-05-10 | — | — | US | claimed |
| EP-2432764-A1 | SUBSTITUTED QUINOLINES FOR USE AS VEGF INHIBITORS | ClanoTech AB (SE) | 2012-03-28 | — | — | EP | disclosed |
| EP-2376456-A2 | HIGHLY PURE LAQUINIMOD OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Actavis Group Ptc Ehf (IS) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010133669-A1 | SUBSTITUTED QUINOLINES FOR USE AS VEGF INHIBITORS | CLANOTECH AB (SE) | 2010-11-25 | — | — | WO | disclosed |
| WO-2010133672-A1 | DERIVATIVES OF QUINOLINE-3-CARBOXYLIC ACID AND THEIR MEDICAL USE | CLANOTECH AB (SE) | 2010-11-25 | — | — | WO | disclosed |
| WO-2010070449-A2 | HIGHLY PURE LAQUINIMOD OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ACTAVIS GROUP PTC EHF (IS) | 2010-06-24 | — | — | WO | disclosed |
| EP-0429627-B1 | DERIVATIVES OF QUINOLINE-3-CARBOXANILIDE | PHARMACIA AB REG NUMBER 556131 (SE) | 1995-09-13 | — | — | EP | disclosed |
| US-5310913-A | Immunomodulators | KABI PHARMACIA AKTIEBOLAG (SE) | 1994-05-10 | — | — | US | disclosed |
| EP-0429627-A1 | DERIVATIVES OF QUINOLINE-3-CARBOXANILIDE. | PHARMACIA AB (SE) | 1991-06-05 | — | — | EP | disclosed |
| WO-1990015052-A1 | DERIVATIVES OF QUINOLINE-3-CARBOXANILIDE | PHARMACIA AB (SE) | 1990-12-13 | — | — | WO | disclosed |
| EP-0059698-A1 | Heterocyclic carboxamides, compositions containing such compounds, processes for their preparation and methods of treatment therewith | AB LEO (SE) | 1982-09-08 | — | — | EP | disclosed |