Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | IDE | P14735 | 1/20 | 0.46 |
| ▸ | MPI | P34949 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | KDM5A | P29375 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9182411 | 0.89 | KDM4E (0.52) | KDM4EALDH1A1MAPTGAAKMT2A | |
| SCHEMBL11282853 | 0.89 | KDM4E (0.52) | KDM4EALDH1A1MAPTGAAKMT2A | |
| SCHEMBL852747 | 0.89 | KMT2A (0.55) | KDM4EALDH1A1MAPTGAAKMT2A | |
| SCHEMBL11291469 | 0.86 | KMT2A (0.50) | KDM4EALDH1A1MAPTGAAKMT2A | |
| SCHEMBL11983217 | 0.86 | KDM4E (0.50) | KDM4EALDH1A1MAPTGAAKMT2A | |
| SCHEMBL11284520 | 0.85 | KDM4E (0.55) | KDM4EALDH1A1MAPTGAAKMT2A | |
| SCHEMBL9186522 | 0.84 | KDM4E (0.51) | KDM4EALDH1A1MAPTGAAKMT2A | |
| SCHEMBL11983191 | 0.84 | KDM4E (0.51) | KDM4EALDH1A1MAPTGAAKMT2A | |
| SCHEMBL11983188 | 0.84 | KDM4E (0.48) | KDM4EALDH1A1MAPTGAAKMT2A | |
| SCHEMBL11983213 | 0.83 | L3MBTL1 (0.53) | KDM4EALDH1A1MAPTGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0059698-A1 | Heterocyclic carboxamides, compositions containing such compounds, processes for their preparation and methods of treatment therewith | AB LEO (SE) | 1982-09-08 | — | — | EP | disclosed |