Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.44 |
| ▸ | ESR1 | P03372 | 6/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.42 |
| ▸ | EBP | Q15125 | 2/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | EBPL | Q9BY08 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8501518 | 0.80 | ESR1 (0.56) | ESR1ESR2 | |
| SCHEMBL8504742 | 0.79 | ESR1 (0.49) | SIGMAR1ESR1ESR2EBPTMEM97 | |
| SCHEMBL8480534 | 0.79 | ESR1 (0.49) | SIGMAR1ESR1ESR2EBPTMEM97 | |
| SCHEMBL8480537 | 0.79 | ESR1 (0.49) | SIGMAR1ESR1ESR2EBPTMEM97 | |
| SCHEMBL8480530 | 0.79 | ESR1 (0.49) | SIGMAR1ESR1ESR2EBPTMEM97 | |
| SCHEMBL8475681 | 0.75 | ESR1 (0.58) | SIGMAR1ESR1ESR2EBPTMEM97 | |
| SCHEMBL8501732 | 0.75 | ESR1 (0.58) | SIGMAR1ESR1ESR2EBPTMEM97 | |
| SCHEMBL8475692 | 0.75 | ESR1 (0.58) | SIGMAR1ESR1ESR2EBPTMEM97 | |
| SCHEMBL8475684 | 0.75 | ESR1 (0.58) | SIGMAR1ESR1ESR2EBPTMEM97 | |
| SCHEMBL8475549 | 0.68 | ESR1 (0.56) | ESR1ESR2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937061-A1 | NOVEL $i(CIS)-3,4-CHROMAN DERIVATIVES USEFUL IN THE PREVENTION OR TREATMENT OF ESTROGEN RELATED DISEASES OR SYNDROMES | NOVO NORDISK A/S (DK) | 1999-08-25 | — | — | EP | claimed |
| WO-1998018777-A1 | NOVEL CIS-3,4-CHROMAN DERIVATIVES USEFUL IN THE PREVENTION OR TREATMENT OF ESTROGEN RELATED DISEASES OR SYNDROMES | NOVO NORDISK A/S (DK) | 1998-05-07 | — | — | WO | claimed |