SCHEMBL8527897

SCHEMBL8527897

[C]OCc1cccc2ccccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.52
CYP2C19 P33261 2/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2D6 P10635 1/20 0.48
CNR1 P21554 1/20 0.47
CNR2 P34972 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
KMT2A Q03164 3/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
MEN1 O00255 2/20 0.46
PARP10 Q53GL7 1/20 0.46
ACP3 P15309 1/20 0.46
SLC1A3 P43003 1/20 0.45
SLC1A2 P43004 1/20 0.45
SLC1A1 P43005 1/20 0.45
HPGD P15428 1/20 0.45
ATM Q13315 1/20 0.44
FFAR1 O14842 1/20 0.43
AKR1B1 P15121 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4850585 0.82 CYP1A2 (0.56) CYP1A2CYP2C19CYP2C9CYP2D6CNR1
SCHEMBL31012122 0.82 CYP1A2 (0.56) CYP1A2CYP2C19CYP2C9CYP2D6CNR1
SCHEMBL2134297 0.78 CYP1A2 (0.52) CYP1A2CYP2C19CYP2C9CYP2D6CNR1
SCHEMBL28480565 0.78 MEN1 (0.54) CYP1A2CYP2C19CYP2C9CYP2D6CNR1
SCHEMBL2093807 0.78 CYP1A2 (0.52) CYP1A2CYP2C19CYP2C9CYP2D6CNR1
SCHEMBL1520903 0.78 IDO1 (0.52) CYP1A2CYP2C19CYP2C9CYP2D6KMT2A
SCHEMBL8726087 0.78 CYP1A2 (0.52) CYP1A2CYP2C19CYP2C9CYP2D6CNR1
SCHEMBL792004 0.78 CYP1A2 (0.53) CYP1A2CYP2C19CYP2C9CYP2D6CNR1
SCHEMBL20827646 0.78 CYP1A2 (0.52) CYP1A2CYP2C19CYP2C9CYP2D6CNR1
Hydroxyamine SCHEMBL8924246 0.77 MEN1 (0.53) CYP1A2CYP2C19CYP2C9CYP2D6CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0938479-A1 QUATERNARY NITROGEN HETEROCYCLES, METHOD FOR THEIR PRODUCTION AND THEIR USE AS PESTICIDES Hoechst Schering AgrEvo GmbH (DE) 1999-09-01 EP disclosed
WO-1998022445-A1 QUATERNARY NITROGEN HETEROCYCLES, METHOD FOR THEIR PRODUCTION AND THEIR USE AS PESTICIDES HOECHST SCHERING AGREVO GMBH (DE) 1998-05-28 WO disclosed