Hydroxyamine

Hydroxyamine

SCHEMBL8924246

NO.c1ccc2c(COCc3cccc4ccccc34)cccc2c1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
PARP10 Q53GL7 1/20 0.53
SLC1A3 P43003 1/20 0.51
SLC1A2 P43004 1/20 0.51
SLC1A1 P43005 1/20 0.51
HSP90AB1 P08238 1/20 0.51
CYP1A2 P05177 2/20 0.50
CYP2C19 P33261 2/20 0.50
CYP2C9 P11712 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
HPGD P15428 1/20 0.49
HTT P42858 1/20 0.49
CA2 P00918 1/20 0.49
ACP3 P15309 1/20 0.48
CYP2D6 P10635 1/20 0.47
CNR1 P21554 1/20 0.46
CNR2 P34972 1/20 0.46
ATM Q13315 1/20 0.46
MTNR1A P48039 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31012122 0.94 CYP1A2 (0.56) MEN1KMT2APARP10SLC1A3SLC1A2
SCHEMBL4850585 0.94 CYP1A2 (0.56) MEN1KMT2APARP10SLC1A3SLC1A2
Sulfuric Acid SCHEMBL28586052 0.86 TDP1 (0.50) MEN1KMT2APARP10SLC1A3SLC1A2
SCHEMBL9707213 0.84 TSHR (0.58) MEN1KMT2ASLC1A3SLC1A2SLC1A1
SCHEMBL4614172 0.82 HTR1B (0.53) MEN1KMT2APARP10SLC1A3SLC1A2
SCHEMBL29641182 0.82 HTR1B (0.53) MEN1KMT2APARP10SLC1A3SLC1A2
SCHEMBL10884842 0.82 TDP1 (0.46) MEN1KMT2APARP10SLC1A3SLC1A2
SCHEMBL2108040 0.82 CYP1A2 (0.48) MEN1KMT2APARP10SLC1A3SLC1A2
SCHEMBL327701 0.82 CYP1A2 (0.50) MEN1KMT2APARP10SLC1A3SLC1A2
SCHEMBL10815296 0.82 CYP1A2 (0.48) MEN1KMT2APARP10SLC1A3SLC1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5625067-A Cyclopentane ether derivatives, processes for their production, and their pharmaceutical use SCHERING AKTIENGESELLSCHAFT (DE) 1997-04-29 US disclosed