SCHEMBL8527908

SCHEMBL8527908

COOC1(C(=O)O)CCCCC1

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.37
FFAR3 O14843 1/20 0.35
NPSR1 Q6W5P4 1/20 0.34
AKR1C1 Q04828 1/20 0.30
USP2 O75604 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
CYP1A2 P05177 1/20 0.30
TSHR P16473 1/20 0.30
BLM P54132 1/20 0.30
CACNA2D1 P54289 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
CTSK P43235 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19233 0.83 CYP2C19 (0.38) CYP2C19FFAR3NPSR1AKR1C1USP2
Hydrochloric Acid SCHEMBL8362281 0.81 CYP2C19 (0.37) CYP2C19FFAR3NPSR1AKR1C1USP2
SCHEMBL2300431 0.80 FFAR3 (0.38) CYP2C19FFAR3NPSR1AKR1C1TSHR
SCHEMBL29031798 0.79 CYP2C19 (0.32) CYP2C19FFAR3
Hydrochloric Acid SCHEMBL11387822 0.78 FFAR3 (0.36) CYP2C19FFAR3NPSR1AKR1C1
SCHEMBL23406876 0.77 CYP2C19 (0.41) CYP2C19FFAR3AKR1C1USP2ALDH1A1
SCHEMBL8593448 0.75 CYP2C19 (0.39) CYP2C19FFAR3AKR1C1USP2ALDH1A1
SCHEMBL5634851 0.75
SCHEMBL29152542 0.75 CYP2C19 (0.39) CYP2C19FFAR3AKR1C1USP2ALDH1A1
SCHEMBL4655557 0.73 CYP2C19 (0.39) CYP2C19FFAR3USP2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0542411-B1 TETRAHYDROTHIENOPYRIDINE DERIVATIVES, FURO AND PYRROLO ANALOGS THEREOF AND THEIR PREPARATION AND USES FOR INHIBITING BLOOD PLATELET AGGREGATION SANKYO CO (JP) 1998-08-12 EP disclosed
EP-0474227-B2 Functionalized peroxides for polymerization reactions ATOCHEM NORTH AMERICA ELF (US) 1998-06-10 EP disclosed
US-5723562-A BLOCK, GRAFT, AND CONDENSATION POLYMERIZATION; ESTERIFICATION, AMIDATION, ETHERIFICATION, CARBAMYLATION ELF ATOCHEM NORTH AMERICA, INC. (US) 1998-03-03 US disclosed
US-5710213-A POLYMERIZING AN UNSATURATED MONOMER OR GRAFTING AN UNSATURATED POLYMER ELF ATOCHEM NORTH AMERICA, INC. (US) 1998-01-20 US disclosed
US-5710210-A Process for polymer reactions with functionalized peroxides ELF ATOCHEM NORTH AMERICA, INC. (US) 1998-01-20 US disclosed
US-5612439-A REACTING WITH MONOMERS TO FORM POLYCARBONATES, POLYESTERS, POLYAMIDES, POLYUREAS, POLYIMIDES, POLYETHERS, AND POLYURETHANES; CURING, CROSSLINKING ELF ATOCHEM NORTH AMERICA, INC. (US) 1997-03-18 US disclosed
US-5536790-A MOLECULAR WEIGHT CONTROL FOR POLYMERS USING PEROXY COMPOUNDS ELF ATOCHEM NORTH AMERICA, INC. (US) 1996-07-16 US disclosed
US-5534596-A CATALYSTS FOR ADDITION POLYMERIZATION, GRAFT POLYMERIZATION, CURING OF UNSATURATED POLYESTERS ELF ATOCHEM NORTH AMERICA, INC. (US) 1996-07-09 US disclosed
US-5466855-A Functionalized peroxides for polymerization reactions ELF ATOCHEM NORTH AMERICA, INC. (US) 1995-11-14 US disclosed
US-5436242-A Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof for inhibiting blood platelet aggregation SANKYO COMPANY, LIMITED (JP) 1995-07-25 US disclosed
US-5319130-A Monomers for condensation polymers; polyepoxides; addition polymerization initiators; compatibilizers of blends ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-06-07 US disclosed
US-5288726-A Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof and their preparation and uses for inhibiting blood platelet aggregation UBE INDUSTRIES LIMITED (JP) 1994-02-22 US disclosed
EP-0542411-A2 Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof and their preparation and uses for inhibiting blood platelet aggregation Sankyo Company Limited (JP) 1993-05-19 EP disclosed