SCHEMBL8593448

SCHEMBL8593448

[O]OC1(C(=O)O)CCCCC1

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.39
AKR1C1 Q04828 1/20 0.32
USP2 O75604 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
CYP1A2 P05177 1/20 0.32
TSHR P16473 1/20 0.32
BLM P54132 1/20 0.32
CACNA2D1 P54289 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
FFAR3 O14843 1/20 0.32
MAP4K4 O95819 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23406876 0.81 CYP2C19 (0.41) CYP2C19AKR1C1USP2ALDH1A1LMNA
SCHEMBL29152542 0.79 CYP2C19 (0.39) CYP2C19AKR1C1USP2ALDH1A1LMNA
SCHEMBL19233 0.77 CYP2C19 (0.38) CYP2C19AKR1C1USP2ALDH1A1LMNA
SCHEMBL8527908 0.75 CYP2C19 (0.37) CYP2C19AKR1C1USP2ALDH1A1LMNA
Hydrochloric Acid SCHEMBL8362281 0.75 CYP2C19 (0.37) CYP2C19AKR1C1USP2ALDH1A1LMNA
SCHEMBL2300431 0.74 FFAR3 (0.38) CYP2C19AKR1C1TSHRFFAR3
SCHEMBL383938 0.73 CYP2C19 (0.35) CYP2C19
SCHEMBL383939 0.73 CYP2C19 (0.35) CYP2C19AKR1C1
SCHEMBL28148022 0.73 CYP2C19 (0.35) CYP2C19
Hydrochloric Acid SCHEMBL11387822 0.72 FFAR3 (0.36) CYP2C19AKR1C1FFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0474227-B2 Functionalized peroxides for polymerization reactions ATOCHEM NORTH AMERICA ELF (US) 1998-06-10 EP disclosed