SCHEMBL8528006

SCHEMBL8528006

O=C(Br)CC(F)=C(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL689143 0.71
SCHEMBL2194265 0.71
SCHEMBL14269332 0.69
SCHEMBL8529012 0.69
SCHEMBL8530109 0.69
SCHEMBL8105848 0.69
SCHEMBL8557207 0.69
SCHEMBL8531593 0.69
SCHEMBL8615368 0.67 MCL1 (0.40)
SCHEMBL27569659 0.67 HDAC8 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1269136-A Fluoric alkenyl compound and use as insect repellent agent MONSANTO CO (US) 2000-10-11 CN disclosed
EP-0640069-B1 FLUOROALKENYL COMPOUNDS AND THEIR USE AS PEST REPELLENTS MONSANTO CO (US) 1998-11-04 EP disclosed
US-5714517-A NEMATOCIDES, INSECTICIDES MONSANTO COMPANY (US) 1998-02-03 US disclosed
US-5693865-A Fluoroalkenyl compounds and their use as pest repellents MONSANTO COMPANY (US) 1997-12-02 US disclosed
EP-0798285-A2 3,4,4-Trifluoro-3-butenoic acid or its methyl ester MONSANTO COMPANY (US) 1997-10-01 EP disclosed
US-5623084-A INSECTICIDES, MITICIDES MONSANTO COMPANY (US) 1997-04-22 US disclosed
US-5561162-A SYSTEMIC PESTICIDES; NEMATOCIDES; INSECTICIDES; MITICIDES; EFFICIENCY; CROPS MONSANTO COMPANY (US) 1996-10-01 US disclosed
US-5457134-A Controlling nematodes, insects, acarids on plants MONSANTO COMPANY (US) 1995-10-10 US disclosed
EP-0640069-A1 FLUOROALKENYL COMPOUNDS AND THEIR USE AS PEST REPELLENTS MONSANTO COMPANY (US) 1995-03-01 EP disclosed
US-5389680-A Insecticides, nematocides, miticides MONSANTO COMPANY (US) 1995-02-14 US disclosed
WO-1992015555-A2 FLUOROALKENYL COMPOUNDS AND THEIR USE AS PEST REPELLENTS MONSANTO COMPANY (US) 1992-09-17 WO disclosed