SCHEMBL8557207

SCHEMBL8557207

O=C(CC(F)=C(F)F)NNC(=O)CC(F)=C(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8615368 0.79 MCL1 (0.40)
SCHEMBL27569659 0.79 HDAC8 (0.39)
SCHEMBL8348397 0.77
SCHEMBL8482532 0.77 KDM4E (0.40)
SCHEMBL2194265 0.71
SCHEMBL395383 0.71 ALDH1A1 (0.37)
SCHEMBL8781587 0.71 CXCL8 (0.35)
SCHEMBL8556055 0.71 KDM5B (0.46)
SCHEMBL8932166 0.69 ALDH1A1 (0.34)
SCHEMBL8531593 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0640069-B1 FLUOROALKENYL COMPOUNDS AND THEIR USE AS PEST REPELLENTS MONSANTO CO (US) 1998-11-04 EP claimed
US-5457134-A Controlling nematodes, insects, acarids on plants MONSANTO COMPANY (US) 1995-10-10 US claimed
EP-0640069-A1 FLUOROALKENYL COMPOUNDS AND THEIR USE AS PEST REPELLENTS MONSANTO COMPANY (US) 1995-03-01 EP claimed
WO-1992015555-A2 FLUOROALKENYL COMPOUNDS AND THEIR USE AS PEST REPELLENTS MONSANTO COMPANY (US) 1992-09-17 WO claimed
CN-1269136-A Fluoric alkenyl compound and use as insect repellent agent MONSANTO CO (US) 2000-10-11 CN disclosed