Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 13/20 | 0.56 |
| ▸ | PPID | Q08752 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | PPIB | P23284 | 1/20 | 0.42 |
| ▸ | PPIA | P62937 | 1/20 | 0.42 |
| ▸ | PPIG | Q13427 | 1/20 | 0.42 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2034587 | 0.84 | ACACB (0.51) | ACACBPPIDHTTPPIBPPIA | |
| SCHEMBL4426853 | 0.79 | PPID (0.55) | PPIDHTTPPIBPPIAPPIG | |
| SCHEMBL8138307 | 0.78 | PPID (0.69) | PPIDHTTPPIBPPIAPPIG | |
| SCHEMBL8528205 | 0.76 | PPID (0.52) | ACACBPPIDHTTPPIBPPIA | |
| SCHEMBL12505582 | 0.75 | PHGDH (0.51) | ACACBHTTGPR139MEN1KMT2A | |
| SCHEMBL3124464 | 0.75 | PHGDH (0.51) | ACACBHTTGPR139MEN1KMT2A | |
| SCHEMBL3105575 | 0.75 | PHGDH (0.51) | ACACBHTTGPR139MEN1KMT2A | |
| SCHEMBL21274649 | 0.74 | HTT (0.49) | HTTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL6262477 | 0.73 | HTT (0.50) | HTTKDM4EALDH1A1 | |
| SCHEMBL16166309 | 0.73 | POLB (0.57) | PPIDHTTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |