Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 4/20 | 0.52 |
| ▸ | PPIB | P23284 | 1/20 | 0.52 |
| ▸ | PPIA | P62937 | 1/20 | 0.52 |
| ▸ | PPIG | Q13427 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8138307 | 0.87 | PPID (0.69) | PPIDPPIBPPIAPPIGPOLB | |
| SCHEMBL15832153 | 0.85 | NPC1 (0.60) | PPIDPPIBPPIAPPIGCNR1 | |
| SCHEMBL2034584 | 0.84 | PPID (0.57) | PPIDPPIBPPIAPPIGGLA | |
| SCHEMBL2037313 | 0.83 | PPID (0.75) | PPIDPPIBPPIAPPIGGLA | |
| SCHEMBL4426853 | 0.80 | PPID (0.55) | PPIDPPIBPPIAPPIGCNR1 | |
| SCHEMBL24943133 | 0.78 | CNR1 (0.62) | CNR1POLBMAPTACACBRAB9A | |
| SCHEMBL4506493 | 0.78 | CYP4F2 (0.66) | MAPTRAB9AHTT | |
| SCHEMBL579391 | 0.77 | KMT2A (0.65) | CNR1POLBMAPTACACBGLA | |
| SCHEMBL6163414 | 0.77 | LOXL2 (0.49) | PPIDPPIBPPIAPPIGMAPT | |
| SCHEMBL8528212 | 0.76 | ACACB (0.56) | PPIDPPIBPPIAPPIGACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |