Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.49 |
| ▸ | MEN1 | O00255 | 10/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | MB | P02144 | 1/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15819518 | 0.89 | SMN1; SMN2 (0.53) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL8529101 | 0.87 | SMN1; SMN2 (0.55) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL15819639 | 0.86 | SMN1; SMN2 (0.53) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL9739530 | 0.86 | KDM4E (0.48) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL8532084 | 0.84 | MAPT (0.45) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL9449335 | 0.84 | NQO2 (0.56) | SMN1; SMN2L3MBTL1ALDH1A1MAPTRXFP1 | |
| SCHEMBL8531553 | 0.83 | MTNR1A (0.52) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL8531965 | 0.83 | HSP90AA1 (0.50) | SMN1; SMN2HTTALDH1A1MAPTHPGD | |
| SCHEMBL15819513 | 0.82 | SMN1; SMN2 (0.49) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL10815305 | 0.81 | CA1 (0.45) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5749925-A | Dyeing or printing process with new and known cationic 4,5-dihydro-iH-1,2,3-triazolium compounds as dyestuffs and new cationic 4,5-dihydro-1H-1,2,3-triazolium compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1998-05-12 | — | — | US | disclosed |