SCHEMBL8528688

SCHEMBL8528688

CN(C)CC1(C=O)CCCCC1

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 18/20 0.37
SLC6A4 P31645 17/20 0.37
SLC6A2 P23975 13/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3694927 0.98 SLC6A4 (0.34) SLC6A3SLC6A4SLC6A2
SCHEMBL22967696 0.88
SCHEMBL29956234 0.78 SLC6A2 (0.35) SLC6A3SLC6A4SLC6A2
SCHEMBL29956463 0.78
SCHEMBL2387433 0.73
SCHEMBL6586875 0.73
SCHEMBL28865589 0.71
SCHEMBL6587692 0.71
SCHEMBL2236262 0.71 TSHR (0.34)
SCHEMBL29951285 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
EP-0693475-B1 1-Phenyl-3-dimethylamino-propane derivatives having pharmacological activity GRUENENTHAL GMBH (DE) 1998-02-11 EP disclosed
EP-0693475-A1 1-Phenyl-3-dimethylamino-propane derivatives having pharmacological activity Grünenthal GmbH (DE) 1996-01-24 EP disclosed