Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 9/20 | 0.46 |
| ▸ | NPY4R | P50391 | 5/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | PADI6 | Q6TGC4 | 1/20 | 0.41 |
| ▸ | FURIN | P09958 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8525686 | 0.84 | NPY1R (0.52) | NPY1RNPY4RNPY5RNPY2R | |
| Acetic Acid SCHEMBL8526885 | 0.80 | NPY1R (0.51) | NPY1RNPY4RNPY5RNPY2R | |
| SCHEMBL7751922 | 0.80 | NPY1R (0.49) | NPY1RNPY4RNPY5RNPY2R | |
| SCHEMBL4650743 | 0.79 | NPY1R (0.61) | NPY1RNPY4RNPY5RNPY2R | |
| SCHEMBL7038160 | 0.78 | NPY1R (0.61) | NPY1RNPY4RNPY5RMCHR1NPY2R | |
| SCHEMBL8585841 | 0.78 | KMT2A (0.50) | NPY1RNPY4RNPY5RMCHR1 | |
| SCHEMBL8526187 | 0.78 | MCHR1 (0.60) | NPY1RNPY4RNPY5RMCHR1PADI6 | |
| SCHEMBL7059807 | 0.78 | NPY1R (0.71) | NPY1RNPY4RNPY5RMCHR1NPY2R | |
| SCHEMBL6899864 | 0.78 | NPY1R (0.71) | NPY1RNPY4RNPY5RMCHR1NPY2R | |
| SCHEMBL16181256 | 0.77 | NPY1R (0.58) | NPY1RFURIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |