Piperidine

Piperidine

SCHEMBL8528732

C1CCNCC1.OP(O)O

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.69
CXCR4 P61073 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
HIF1A Q16665 1/20 0.36
MAPT P10636 1/20 0.36
PDE4A P27815 1/20 0.36
KDR P35968 1/20 0.36
CA2 P00918 1/20 0.32
CHKA P35790 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Piperidine SCHEMBL27278836 1.00 ALDH1A1 (0.69) ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT
Pyrrolidine SCHEMBL28835057 0.96
Piperidine SCHEMBL29238202 0.86 ALDH1A1 (0.60) ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT
SCHEMBL3498160 0.83 ALDH1A1 (1.00) ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT
Piperidine SCHEMBL21819962 0.83 ALDH1A1 (1.00) ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT
Piperidine SCHEMBL11283826 0.83
Piperidine SCHEMBL8435190 0.83 ALDH1A1 (1.00) ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT
SCHEMBL21753221 0.83 ALDH1A1 (1.00) ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT
Azepane SCHEMBL11361504 0.83
SCHEMBL3071895 0.83 ALDH1A1 (1.00) ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0286478-B1 PHOSPHOROUS-ACID SALTS, THEIR COMMPOSITIONS AND THEIR USE AS FIRE-PROOFING AGENTS ELF ATOCHEM S.A. (FR) 1993-03-10 EP claimed
WO-2013098573-A1 SOIL AND PLANT CONDITIONER PRODUCTS PLANTACO LOGISZTIKAI SZOLGÁLTATÓ KFT. (HU) 2013-07-04 WO disclosed
EP-0651006-B1 Piperidinyl phosphite compositions and polyolefin compositions containing them MONTELL NORTH AMERICA INC (US) 1998-03-11 EP disclosed
US-5607989-A Piperidinyl phosphite compositions and polyolefin compositions containing them MONTELL NORTH AMERICA INC. (US) 1997-03-04 US disclosed
EP-0651006-A1 Piperidinyl phosphite compositions and polyolefin compositions containing them MONTELL NORTH AMERICA INC. (US) 1995-05-03 EP disclosed
CN-1015716-B PHOSPHOROUS ACID MIXING ESTER FOR POLYMERISATION INHIBITOR AND ITS INDUSTRIAL PRODUCING METHOD BEIJING ASISTANT INST (CN) 1992-03-04 CN disclosed
CN-1041598-A The phosphorous acid that stopper is used (2,2,6, the 6-tetramethyl piperidine nitrogen oxygen free radical) mixed ester and industrial process thereof BEIJING ASISTANT INST (CN) 1990-04-25 CN disclosed
US-4762872-A POLYOLEFIN FIBERS, POLY(AMINOACETAMIDES) THE B. F. GOODRICH COMPANY (US) 1988-08-09 US disclosed
EP-0224720-A1 Oligomeric light stabilizers with substituted piperidine ends The B.F. GOODRICH Company (US) 1987-06-10 EP disclosed
US-4293466-A Piperidine phosphite stabilizers for polymers and polymers stabilized thereby MONTEDISON S.P.A. (IT) 1981-10-06 US disclosed