Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.31 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8531406 | 0.87 | L3MBTL1 (0.34) | HRH2HRH1HRH4HRH3TDP1 | |
| SCHEMBL8528811 | 0.83 | HRH3 (0.36) | HRH2HRH1HRH4HRH3TDP1 | |
| SCHEMBL28285468 | 0.80 | HRH3 (0.42) | HRH2HRH1HRH4HRH3TDP1 | |
| SCHEMBL7312965 | 0.75 | HRH3 (0.38) | HRH2HRH1HRH4HRH3TDP1 | |
| SCHEMBL8528267 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL7313845 | 0.73 | TDP1 (0.40) | HRH2HRH1HRH4HRH3TDP1 | |
| SCHEMBL14290737 | 0.72 | HRH3 (0.39) | HRH2HRH1HRH4HRH3TDP1 | |
| SCHEMBL10728091 | 0.71 | HRH3 (0.47) | HRH2HRH1HRH4HRH3TDP1 | |
| SCHEMBL8528671 | 0.70 | L3MBTL1 (0.33) | HRH2HRH1HRH4HRH3TDP1 | |
| SCHEMBL721194 | 0.69 | HRH3 (0.41) | HRH2HRH1HRH4HRH3TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0460679-B1 | Endothelin antagonistic peptide derivatives | BANYU PHARMA CO LTD (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5691315-A | CARDIOVASCULAR DISORDERS; VASODILATOR; BRONCHODILATOR | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5470833-A | Vasodilators, bronchodilators | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-11-28 | — | — | US | disclosed |
| US-5444152-A | Vasolidator or bronchodilator | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-22 | — | — | US | disclosed |
| EP-0460679-A2 | Endothelin antagonistic peptide derivatives | Banyu Pharmaceutical Co., Ltd. (JP) | 1991-12-11 | — | — | EP | disclosed |