SCHEMBL8528814

SCHEMBL8528814

CCC[C@H]1CC[C@H](C2CCC(COc3ccccc3)CC2)CC1

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 1/20 0.47
PRMT6 Q96LA8 1/20 0.47
TDP1 Q9NUW8 1/20 0.42
RIPK1 Q13546 1/20 0.42
DRD2 P14416 1/20 0.41
DRD4 P21917 1/20 0.41
PARP15 Q460N3 1/20 0.41
PARP10 Q53GL7 1/20 0.41
PARP2 Q9UGN5 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8528819 1.00 CARM1 (0.47) CARM1PRMT6TDP1RIPK1DRD2
SCHEMBL8078580 1.00 CARM1 (0.47) CARM1PRMT6TDP1RIPK1DRD2
SCHEMBL9259082 0.95 CARM1 (0.50) CARM1PRMT6TDP1RIPK1DRD2
SCHEMBL8042599 0.95 CARM1 (0.50) CARM1PRMT6TDP1RIPK1DRD2
SCHEMBL9346506 0.87 TEAD1 (0.47)
SCHEMBL9346498 0.87 TEAD1 (0.47)
SCHEMBL9344646 0.87 CARM1 (0.49) CARM1PRMT6TDP1DRD2DRD4
SCHEMBL9344650 0.87 CARM1 (0.49) CARM1PRMT6TDP1DRD2DRD4
SCHEMBL9344655 0.87 CARM1 (0.49) CARM1PRMT6TDP1DRD2DRD4
SCHEMBL13110604 0.86 PARP15 (0.43) TDP1PARP15PARP10PARP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0733610-B1 Liquid crystalline compound, liquid crystal composition containing the same and liquid crystal display device CHISSO CORP (JP) 1998-10-28 EP disclosed
EP-0597701-B1 Conjugated enyne derivative and liquid crystal composition CHISSO CORP (JP) 1997-04-16 EP disclosed
EP-0733610-A1 Liquid crystalline compound, liquid crystal composition containing the same and liquid crystal display device Chisso Corporation (JP) 1996-09-25 EP disclosed
EP-0393636-B1 Liquid crystal composition and liquid crystal display using said composition CHISSO CORP (JP) 1994-07-20 EP disclosed
EP-0597701-A1 Conjugated enyne derivative and liquid crystal composition CHISSO CORPORATION (JP) 1994-05-18 EP disclosed
US-5258135-A Multiplexed displays, supertwisted birefringence effect CHISSO CORPORATION (JP) 1993-11-02 US disclosed
EP-0318003-B1 A liquid crystal composition for twist nematic mode CHISSO CORP (JP) 1993-10-20 EP disclosed
EP-0432780-B1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAID COMPOSITION CHISSO CORPORATION (JP) 1993-07-21 EP disclosed
EP-0364588-B1 LIQUID CRYSTAL COMPOSITION CHISSO CORPORATION (JP) 1993-02-10 EP disclosed
US-5102577-A Supertwisted birefringence system CHISSO CORPORATION (JP) 1992-04-07 US disclosed
EP-0432780-A1 Liquid crystal composition and liquid crystal display using said composition CHISSO CORPORATION (JP) 1991-06-19 EP disclosed
EP-0393636-A2 Liquid crystal composition and liquid crystal display using said composition CHISSO CORPORATION (JP) 1990-10-24 EP disclosed
EP-0318003-A2 A liquid crystal composition for twist nematic mode CHISSO CORPORATION (JP) 1989-05-31 EP disclosed