Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.50 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8042599 | 1.00 | CARM1 (0.50) | CARM1PRMT6TDP1RIPK1PARP15 | |
| SCHEMBL8078580 | 0.95 | CARM1 (0.47) | CARM1PRMT6TDP1RIPK1PARP15 | |
| SCHEMBL8528814 | 0.95 | CARM1 (0.47) | CARM1PRMT6TDP1RIPK1PARP15 | |
| SCHEMBL8528819 | 0.95 | CARM1 (0.47) | CARM1PRMT6TDP1RIPK1PARP15 | |
| SCHEMBL1990800 | 0.87 | TDP1 (0.57) | CARM1PRMT6TDP1PARP15PARP10 | |
| SCHEMBL8081852 | 0.86 | LTA4H (0.50) | — | |
| SCHEMBL8529857 | 0.86 | LTA4H (0.50) | — | |
| SCHEMBL9344709 | 0.84 | LTA4H (0.53) | DRD2 | |
| SCHEMBL9344705 | 0.84 | LTA4H (0.53) | DRD2 | |
| SCHEMBL11312915 | 0.84 | PARP15 (0.46) | TDP1PARP15PARP10PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5454975-A | Electrooptical display | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-10-03 | — | — | US | disclosed |
| EP-0308747-B1 | TOLAN COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | CHISSO CORPORATION (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-4895672-A | Tolan compound and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1990-01-23 | — | — | US | disclosed |
| EP-0308747-A2 | Tolan compound and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1989-03-29 | — | — | EP | disclosed |