Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8532596 | 0.85 | KMT2A (0.49) | SMN1; SMN2KMT2AMEN1CYP3A4CYP2D6 | |
| SCHEMBL8528832 | 0.84 | KMT2A (0.61) | SMN1; SMN2TSHRKMT2AMEN1CYP3A4 | |
| SCHEMBL14318726 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2TSHRKMT2AMEN1HTT | |
| SCHEMBL17227851 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2TSHRKMT2AMEN1HTT | |
| SCHEMBL8527698 | 0.81 | NPSR1 (0.45) | SMN1; SMN2KMT2AMEN1CYP3A4CYP2D6 | |
| SCHEMBL14318729 | 0.81 | KMT2A (0.67) | SMN1; SMN2KMT2AMEN1HTTL3MBTL1 | |
| SCHEMBL8530608 | 0.80 | KMT2A (0.48) | SMN1; SMN2KMT2AMEN1CYP3A4CYP2D6 | |
| SCHEMBL8531842 | 0.79 | GAA (0.68) | SMN1; SMN2KMT2AMEN1HTTRAB9A | |
| SCHEMBL3307790 | 0.79 | KMT2A (0.60) | TSHRKMT2AMEN1STAT3ALDH1A1 | |
| SCHEMBL8531486 | 0.77 | IDO1 (0.58) | SMN1; SMN2KMT2AMEN1STAT3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0460679-B1 | Endothelin antagonistic peptide derivatives | BANYU PHARMA CO LTD (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5691315-A | CARDIOVASCULAR DISORDERS; VASODILATOR; BRONCHODILATOR | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5470833-A | Vasodilators, bronchodilators | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-11-28 | — | — | US | disclosed |
| US-5444152-A | Vasolidator or bronchodilator | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-22 | — | — | US | disclosed |
| EP-0460679-A2 | Endothelin antagonistic peptide derivatives | Banyu Pharmaceutical Co., Ltd. (JP) | 1991-12-11 | — | — | EP | disclosed |