Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | STAT3 | P40763 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3307790 | 0.85 | KMT2A (0.60) | KMT2AMEN1STAT3ALDH1A1KDM4E | |
| SCHEMBL8531486 | 0.83 | IDO1 (0.58) | KMT2AMEN1SMN1; SMN2STAT3L3MBTL1 | |
| SCHEMBL8532596 | 0.83 | KMT2A (0.49) | KMT2AMEN1SMN1; SMN2STAT3CYP3A4 | |
| SCHEMBL8531842 | 0.83 | GAA (0.68) | KMT2AMEN1SMN1; SMN2HTTRAB9A | |
| SCHEMBL8530610 | 0.81 | KMT2A (0.69) | KMT2AMEN1SMN1; SMN2STAT3CYP3A4 | |
| SCHEMBL8528830 | 0.80 | SMN1; SMN2 (0.47) | KMT2AMEN1SMN1; SMN2STAT3CYP3A4 | |
| SCHEMBL8528642 | 0.80 | ALDH1A1 (0.67) | KMT2AMEN1SMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL9703067 | 0.80 | KMT2A (0.48) | KMT2AMEN1SMN1; SMN2STAT3CYP3A4 | |
| SCHEMBL8530927 | 0.79 | GAA (0.49) | KMT2AMEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL28555490 | 0.79 | CDC25A (0.51) | KMT2AMEN1SMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0460679-B1 | Endothelin antagonistic peptide derivatives | BANYU PHARMA CO LTD (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5691315-A | CARDIOVASCULAR DISORDERS; VASODILATOR; BRONCHODILATOR | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5470833-A | Vasodilators, bronchodilators | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-11-28 | — | — | US | disclosed |