Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.55 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | FDPS | P14324 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8597910 | 0.76 | ANPEP (0.61) | ANPEPERAP2MAPTATMMEN1 | |
| SCHEMBL13024066 | 0.74 | MEN1 (0.70) | ANPEPERAP2MAPTATMMEN1 | |
| SCHEMBL8675612 | 0.74 | ANPEP (0.64) | ANPEPERAP2MAPTATMMEN1 | |
| SCHEMBL8991677 | 0.74 | ANPEP (0.64) | ANPEPERAP2MAPTATMMEN1 | |
| SCHEMBL8712070 | 0.72 | ANPEP (0.52) | ANPEPERAP2MAPTATMMEN1 | |
| SCHEMBL8714200 | 0.71 | ANPEP (0.55) | ANPEPERAP2MAPTATMMEN1 | |
| SCHEMBL9463733 | 0.70 | MEN1 (0.64) | ANPEPERAP2MAPTATMMEN1 | |
| SCHEMBL8671774 | 0.69 | ANPEP (0.53) | ANPEPERAP2MAPTATMMEN1 | |
| SCHEMBL8928300 | 0.69 | ANPEP (0.47) | ANPEPERAP2MAPTATMMEN1 | |
| SCHEMBL20088212 | 0.69 | MAPT (0.56) | ANPEPERAP2MAPTATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5730715-A | BONE DISORDERS | BECTON DICKINSON AND COMPANY (US) | 1998-03-24 | — | — | US | disclosed |