Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.64 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | FDPS | P14324 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991677 | 1.00 | ANPEP (0.64) | ANPEPERAP2MAPTMEN1KMT2A | |
| SCHEMBL8597910 | 0.98 | ANPEP (0.61) | ANPEPERAP2MAPTMEN1KMT2A | |
| SCHEMBL8671774 | 0.90 | ANPEP (0.53) | ANPEPERAP2MAPTMEN1KMT2A | |
| SCHEMBL10714751 | 0.78 | FDPS (0.50) | ANPEPERAP2MAPTFDPSGAA | |
| SCHEMBL9081590 | 0.78 | ANPEP (0.50) | ANPEPERAP2MAPTMEN1KMT2A | |
| SCHEMBL8671777 | 0.77 | ANPEP (0.45) | ANPEPERAP2MAPTMEN1KMT2A | |
| SCHEMBL3739664 | 0.76 | ANPEP (0.47) | ANPEPERAP2MAPTFDPSCA12 | |
| SCHEMBL8672081 | 0.75 | MEN1 (0.41) | ANPEPERAP2MAPTMEN1KMT2A | |
| SCHEMBL8528864 | 0.74 | ANPEP (0.55) | ANPEPERAP2MAPTMEN1KMT2A | |
| SCHEMBL8672135 | 0.74 | KDM4E (0.55) | ANPEPERAP2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0608322-B1 | ENHANCED SKIN PENETRATION SYSTEM FOR IMPROVED TOPICAL DELIVERY OF DRUGS | RICHARDSON VICKS INC (US) | 1998-07-22 | — | — | EP | claimed |
| US-5773023-A | BLEND OF AQUEOUS CARRIER, ACTIVE MATERIAL AND POLYACRYLAMIDE | RICHARDSON-VICKS INC. (US) | 1998-06-30 | — | — | US | claimed |
| EP-0608320-B1 | ENHANCED SKIN PENETRATION SYSTEM FOR IMPROVED TOPICAL DELIVERY OF DRUGS | RICHARDSON VICKS INC (US) | 1998-01-28 | — | — | EP | claimed |
| EP-0652774-B1 | PHARMACEUTICAL COMPOSITION FOR TOPICAL USE CONTAINING A CROSSLINKED CATIONIC POLYMER AND AN ALKOXYLATED ETHER | PROCTER & GAMBLE (US) | 1997-05-07 | — | — | EP | claimed |
| US-5614178-A | TRANSDERMAL | THE PROCTER & GAMBLE COMPANY (US) | 1997-03-25 | — | — | US | claimed |
| EP-0722268-A1 | HERBICIDAL AZA BISPHOSPHONIC ACID COMPOSITIONS | ZENECA LIMITED (GB) | 1996-07-24 | — | — | EP | claimed |
| EP-0652774-A1 | PHARMACEUTICAL COMPOSITION FOR TOPICAL USE CONTAINING A CROSSLINKED CATIONIC POLYMER AND AN ALKOXYLATED ETHER. | PROCTER & GAMBLE (US) | 1995-05-17 | — | — | EP | claimed |
| WO-1995010188-A2 | HERBICIDAL AZA BISPHOSPHONIC ACID COMPOSITIONS | ZENECA LIMITED (GB) | 1995-04-20 | — | — | WO | claimed |
| EP-0608322-A1 | ENHANCED SKIN PENETRATION SYSTEM FOR IMPROVED TOPICAL DELIVERY OF DRUGS | RICHARDSON-VICKS, INC. (US) | 1994-08-03 | — | — | EP | claimed |
| EP-0608320-A1 | ENHANCED SKIN PENETRATION SYSTEM FOR IMPROVED TOPICAL DELIVERY OF DRUGS | RICHARDSON-VICKS, INC. (US) | 1994-08-03 | — | — | EP | claimed |
| EP-0274158-B1 | Novel heterocycle-substituted diphosphonate compounds, pharmaceutical compositions, and methods of treating abnormal calcium and phosphate matabolism | NORWICH EATON PHARMA (US) | 1994-03-23 | — | — | EP | claimed |
| WO-1994002176-A1 | PHARMACEUTICAL COMPOSITION FOR TOPICAL USE CONTAINING A CROSSLINKED CATIONIC POLYMER AND AN ALKOXYLATED ETHER | THE PROCTER & GAMBLE COMPANY (US) | 1994-02-03 | — | — | WO | claimed |
| WO-1993007902-A1 | ENHANCED SKIN PENETRATION SYSTEM FOR IMPROVED TOPICAL DELIVERY OF DRUGS | RICHARDSON-VICKS, INC. (US) | 1993-04-29 | — | — | WO | claimed |
| WO-1993007903-A1 | ENHANCED SKIN PENETRATION SYSTEM FOR IMPROVED TOPICAL DELIVERY OF DRUGS | RICHARDSON-VICKS, INC. (US) | 1993-04-29 | — | — | WO | claimed |
| US-5728650-A | Herbicidal aza bisphosphonic acids and compositions containing the same | ZENECA LIMITED (GB) | 1998-03-17 | — | — | US | disclosed |
| EP-0722268-A1 | HERBICIDAL AZA BISPHOSPHONIC ACID COMPOSITIONS | ZENECA LIMITED (GB) | 1996-07-24 | — | — | EP | disclosed |
| US-5519013-A | Heterocycle-substituted diphosphonate compounds, pharmaceutical compositions, and methods of treating abnormal calcium and phosphate metabolism | THE PROCTER & GAMBLE COMPANY (US) | 1996-05-21 | — | — | US | disclosed |
| WO-1992021355-A1 | CALCIUM, TRACE MINERAL, VITAMIN D AND DRUG THERAPY COMBINATIONS | THE PROCTER & GAMBLE COMPANY (US) | 1992-12-10 | — | — | WO | disclosed |
| US-5071840-A | Certain heterocyclic substituted diphosphonate compounds pharmaceutical compositions, and methods of treating abnormal calcium and phosphate metabolism | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1991-12-10 | — | — | US | disclosed |
| EP-0351897-A2 | Skin penetration system for salts of amine-functional drugs | THE PROCTER & GAMBLE COMPANY (US) | 1990-01-24 | — | — | EP | disclosed |