Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1639680 | 0.77 | ACE2 (0.40) | ACE2 | |
| SCHEMBL9717661 | 0.77 | ESR1 (0.32) | ESR1ESR2ACE2 | |
| SCHEMBL28004141 | 0.76 | CYP3A4 (0.31) | — | |
| SCHEMBL20036963 | 0.76 | — | — | |
| SCHEMBL30949372 | 0.74 | — | — | |
| Alcohol SCHEMBL9874585 | 0.72 | ACE2 (0.31) | ACE2 | |
| SCHEMBL30949375 | 0.71 | ACE2 (0.33) | ACE2 | |
| SCHEMBL30949364 | 0.70 | — | — | |
| SCHEMBL30949370 | 0.69 | ACE2 (0.38) | ACE2 | |
| SCHEMBL22719764 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101863971-A | Metastin derivatives and use thereof | TAKEDA PHARMACEUTICAL | 2010-10-20 | — | — | CN | disclosed |
| CN-101845091-A | Metastin derivative and use thereof | TAKEDA PHARMACEUTICAL | 2010-09-29 | — | — | CN | disclosed |
| CN-1972959-A | Metastin derivative and use thereof | TAKEDA PHARMACEUTICAL (JP) | 2007-05-30 | — | — | CN | disclosed |
| CN-1419563-A | Peptide derivative | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-21 | — | — | CN | disclosed |
| CN-1328568-A | Peptide derivatives | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-12-26 | — | — | CN | disclosed |
| CN-1219953-A | Fabric softening compound/composition | PROCTER & GAMBLE (US) | 1999-06-16 | — | — | CN | disclosed |
| CN-1196082-A | Concentrated stable fabric softening compositions comprising chelants | PROCTER & GAMBLE (US) | 1998-10-14 | — | — | CN | disclosed |
| US-5747443-A | BIODEGRADABLE QUATERNARY AMMONIUM COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 1998-05-05 | — | — | US | disclosed |