Known targets — ChEMBL curated mechanism
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The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9717661 | 0.94 | ESR1 (0.32) | ACE2 | |
| SCHEMBL8528946 | 0.72 | ESR1 (0.32) | ACE2 | |
| SCHEMBL10768111 | 0.70 | ACE2 (0.37) | ACE2 | |
| SCHEMBL9451059 | 0.67 | ALDH1A1 (0.32) | — | |
| SCHEMBL21955590 | 0.67 | HTT (0.31) | — | |
| SCHEMBL10981818 | 0.65 | ALDH1A1 (0.30) | — | |
| SCHEMBL9501251 | 0.65 | — | — | |
| SCHEMBL10981816 | 0.63 | ALDH1A1 (0.30) | — | |
| SCHEMBL149482 | 0.62 | — | — | |
| SCHEMBL9451066 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992416-A | Perfumes | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1991-02-12 | — | — | US | disclosed |