SCHEMBL8528971

SCHEMBL8528971

c1ccc2c(c1)OCC1CNCCC21

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.44
DRD3 P35462 1/20 0.44
HTR6 P50406 3/20 0.38
SSTR4 P31391 1/20 0.35
LTB4R Q15722 1/20 0.35
LTB4R2 Q9NPC1 1/20 0.35
HTR2B P41595 1/20 0.34
HTR2C P28335 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29960168 0.98 DRD2 (0.43) DRD2DRD3HTR6SSTR4LTB4R
Hydrochloric Acid SCHEMBL29960332 0.98 DRD2 (0.43) DRD2DRD3HTR6SSTR4LTB4R
SCHEMBL30849006 0.91 DRD2 (0.43) DRD2DRD3SSTR4LTB4RLTB4R2
SCHEMBL10717880 0.87 DRD2 (0.44) DRD2DRD3HTR6SSTR4LTB4R
SCHEMBL10717883 0.87 DRD2 (0.44) DRD2DRD3HTR6SSTR4LTB4R
SCHEMBL6245152 0.85 DRD2 (0.48) DRD2DRD3SSTR4LTB4RLTB4R2
SCHEMBL29960480 0.85 DRD2 (0.48) DRD2DRD3SSTR4LTB4RLTB4R2
SCHEMBL7847793 0.85 DRD2 (0.48) DRD2DRD3SSTR4LTB4RLTB4R2
SCHEMBL7846708 0.85 DRD2 (0.48) DRD2DRD3SSTR4LTB4RLTB4R2
SCHEMBL7846711 0.85 DRD2 (0.48) DRD2DRD3SSTR4LTB4RLTB4R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025078808-A1 NOVEL COMPOUNDS SITRYX THERAPEUTICS LIMITED (GB) 2025-04-17 WO disclosed
EP-0942911-A1 BENZOPYRANOPYRROLE AND BENZOPYRANOPYRIDINE ALPHA-1 ADRENERGIC COMPOUNDS Abbott Laboratories (US) 1999-09-22 EP disclosed
WO-1998024791-A1 BENZOPYRANOPYRROLE AND BENZOPYRANOPYRIDINE ALPHA-1 ADRENERGIC COMPOUNDS ABBOTT LABORATORIES (US) 1998-06-11 WO disclosed