Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 7/20 | 0.45 |
| ▸ | FDPS | P14324 | 14/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8866988 | 0.94 | FDPS (0.40) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL8745035 | 0.90 | GGPS1 (0.37) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL8531359 | 0.85 | FOLH1 (0.36) | — | |
| SCHEMBL8528293 | 0.84 | FDPS (0.42) | FDPSSMPD1 | |
| SCHEMBL8532196 | 0.83 | FOLH1 (0.37) | — | |
| SCHEMBL9486308 | 0.82 | GGPS1 (0.59) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL4267775 | 0.82 | GGPS1 (0.59) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL8529495 | 0.81 | FOLH1 (0.40) | — | |
| SCHEMBL9487614 | 0.81 | GGPS1 (0.57) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL14760426 | 0.81 | FDPS (0.55) | GGPS1FDPSSMPD1LPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0752999-B1 | 2,4-DIPHOSPHONOGLUTARIC ACID DERIVATIVES, METHODS OF PREPARING SUCH COMPOUNDS AND DRUGS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1998-10-28 | — | — | EP | disclosed |
| US-5698541-A | DISEASES OF CALCIUM METABOLISM; OSTEOPOROSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-12-16 | — | — | US | disclosed |