Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9145163 | 1.00 | CYP2C9 (0.38) | CYP2C9CHRM3CHRM2CHRM1CHRM4 | |
| SCHEMBL9146133 | 1.00 | CYP2C9 (0.38) | CYP2C9CHRM3CHRM2CHRM1CHRM4 | |
| SCHEMBL9145099 | 0.85 | CYP2C9 (0.38) | CYP2C9CHRM3CHRM2CHRM1CHRM4 | |
| SCHEMBL4404703 | 0.82 | CYP2C9 (0.40) | CYP2C9CHRM3CHRM2CHRM1CHRM4 | |
| SCHEMBL5712868 | 0.81 | CHRNA7 (0.42) | CYP2C9CHRM3CHRM2CHRM1CHRM4 | |
| SCHEMBL9848240 | 0.76 | CHRM3 (0.33) | CYP2C9CHRM3CHRM2CHRM1CHRM4 | |
| SCHEMBL9145118 | 0.76 | CHRM3 (0.33) | CYP2C9CHRM3CHRM2CHRM1CHRM4 | |
| SCHEMBL9145027 | 0.76 | CHRM3 (0.33) | CYP2C9CHRM3CHRM2CHRM1CHRM4 | |
| SCHEMBL21057815 | 0.76 | CHRM3 (0.34) | CHRM3 | |
| SCHEMBL7648975 | 0.72 | CHRM3 (0.43) | CHRM3CHRM2CHRM1CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648130-B1 | RADIOIODINATED BENZOVESAMICOL ANALOGS FOR CHOLINERGIC NERVE MAPPING | UNIV MICHIGAN (US) | 1998-12-30 | — | — | EP | disclosed |
| EP-0648130-A1 | RADIOIODINATED BENZOVESAMICOL ANALOGS FOR CHOLINERGIC NERVE MAPPING | THE UNIVERSITY OF MICHIGAN (US) | 1995-04-19 | — | — | EP | disclosed |
| EP-0648130-A4 | RADIOIODINATED BENZOVESAMICOL ANALOGS FOR CHOLINERGIC NERVE MAPPING. | UNIV MICHIGAN (US) | 1994-01-26 | — | — | EP | disclosed |
| US-5077035-A | Scintigraphic imaging of brain; Alzheimer*s diagnosis | THE UNIVERSITY OF MICHIGAN (US) | 1991-12-31 | — | — | US | disclosed |
| WO-1991017776-A1 | RADIOIODINATED BENZOVESAMICOL ANALOGS FOR CHOLINERGIC NERVE MAPPING | THE UNIVERSITY OF MICHIGAN (US) | 1991-11-28 | — | — | WO | disclosed |