Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 6/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9145118 | 1.00 | CHRM3 (0.33) | CHRM3CYP2C9CHRM2CHRM1CHRM4 | |
| SCHEMBL9145027 | 1.00 | CHRM3 (0.33) | CHRM3CYP2C9CHRM2CHRM1CHRM4 | |
| SCHEMBL4404703 | 0.84 | CYP2C9 (0.40) | CHRM3CYP2C9CHRM2CHRM1CHRM4 | |
| SCHEMBL9145099 | 0.82 | CYP2C9 (0.38) | CHRM3CYP2C9CHRM2CHRM1CHRM4 | |
| SCHEMBL21057815 | 0.82 | CHRM3 (0.34) | CHRM3 | |
| SCHEMBL9145091 | 0.77 | CHRM2 (0.46) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL9146133 | 0.76 | CYP2C9 (0.38) | CHRM3CYP2C9CHRM2CHRM1CHRM4 | |
| SCHEMBL8529192 | 0.76 | CYP2C9 (0.38) | CHRM3CYP2C9CHRM2CHRM1CHRM4 | |
| SCHEMBL9145163 | 0.76 | CYP2C9 (0.38) | CHRM3CYP2C9CHRM2CHRM1CHRM4 | |
| SCHEMBL5712868 | 0.76 | CHRNA7 (0.42) | CHRM3CYP2C9CHRM2CHRM1CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441491-A1 | Boronic acid adducts of rhenium dioxime and technetium-99M dioxime complexes containing a biochemically active group | BRACCO INTERNATIONAL B.V. (NL) | 1991-08-14 | — | — | EP | disclosed |