Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 10/20 | 0.68 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | F13A1 | P00488 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21886869 | 0.82 | KAT2B (0.72) | KAT2BKAT2APTGS1PTGS2HSD17B10 | |
| SCHEMBL8533834 | 0.81 | KAT2B (1.00) | KAT2B | |
| SCHEMBL21814603 | 0.80 | KAT2B (0.56) | KAT2BKAT2AKMOCA12CA1 | |
| SCHEMBL9234887 | 0.77 | KAT2B (0.61) | KAT2BKDM4ECA12CA1CA9 | |
| SCHEMBL11193788 | 0.75 | KAT2B (0.97) | KAT2BPTGS1PTGS2HSD17B10CA12 | |
| SCHEMBL9565234 | 0.75 | KAT2B (0.97) | KAT2BPTGS1PTGS2HSD17B10CA12 | |
| SCHEMBL11189889 | 0.73 | KAT2B (0.77) | KAT2BHSD17B10CA12CA1CA9 | |
| SCHEMBL21814437 | 0.72 | KAT2B (0.65) | KAT2BKDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11713957 | 0.72 | KAT2B (0.90) | KAT2BPTGS1PTGS2HSD17B10CA12 | |
| SCHEMBL1533676 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592127-B1 | Immunoassay for isothiazolones | ROHM & HAAS (US) | 1998-04-15 | — | — | EP | disclosed |
| US-5554542-A | Immunoassay for isothiazolones | ROHM AND HAAS COMPANY (US) | 1996-09-10 | — | — | US | disclosed |
| EP-0592127-A1 | Immunoassay for isothiazolones | ROHM AND HAAS COMPANY (US) | 1994-04-13 | — | — | EP | disclosed |