Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 10/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | G6PD | P11413 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9565202 | 0.88 | KAT2B (0.79) | KAT2BALDH1A1TSHRCA12CA1 | |
| SCHEMBL8529337 | 0.82 | KAT2B (0.68) | KAT2BCA12CA1CA9PTGS1 | |
| SCHEMBL11193788 | 0.80 | KAT2B (0.97) | KAT2BALDH1A1TSHRCA12CA1 | |
| SCHEMBL9565234 | 0.80 | KAT2B (0.97) | KAT2BALDH1A1TSHRCA12CA1 | |
| SCHEMBL8062252 | 0.80 | KAT2B (0.97) | KAT2BALDH1A1TSHRCA12CA1 | |
| Hydrochloric Acid SCHEMBL11713957 | 0.77 | KAT2B (0.90) | KAT2BALDH1A1TSHRCA12CA1 | |
| Hydrochloric Acid SCHEMBL10496287 | 0.77 | KAT2B (0.90) | KAT2BALDH1A1TSHRCA12CA1 | |
| SCHEMBL8533834 | 0.77 | KAT2B (1.00) | KAT2BALDH1A1TSHR | |
| SCHEMBL9255667 | 0.77 | KAT2B (0.69) | KAT2BALDH1A1CA12CA1CA9 | |
| SCHEMBL21814437 | 0.77 | KAT2B (0.65) | KAT2BALDH1A1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020065408-A1 | SULFOMALEIMIDE-BASED LINKERS AND CORRESPONDING CONJUGATES | PIERRE FABRE MEDICAMENT (FR) | 2020-04-02 | — | — | WO | disclosed |