Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 3/20 | 0.49 |
| ▸ | PLAU | P00749 | 2/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.49 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1740223 | 1.00 | PLG (0.49) | PLGPLAUF10KLKB1ITGB3 | |
| SCHEMBL7020069 | 0.94 | PLG (0.49) | PLGPLAUF10KLKB1ITGB3 | |
| SCHEMBL26907175 | 0.91 | PLG (0.45) | PLGPLAUF10KLKB1ITGB3 | |
| SCHEMBL5141894 | 0.91 | PLG (0.45) | PLGPLAUF10KLKB1ITGB3 | |
| SCHEMBL1323026 | 0.91 | PLG (0.45) | PLGPLAUF10KLKB1ITGB3 | |
| SCHEMBL30822847 | 0.91 | PLG (0.45) | PLGPLAUF10KLKB1ITGB3 | |
| SCHEMBL29406228 | 0.91 | PLG (0.45) | PLGPLAUF10KLKB1ITGB3 | |
| Hydrochloric Acid SCHEMBL1711200 | 0.90 | PLG (0.44) | PLGPLAUF10KLKB1ITGB3 | |
| SCHEMBL8526287 | 0.85 | PLG (0.48) | PLGPLAUF10KLKB1ITGB3 | |
| SCHEMBL8526793 | 0.85 | PLG (0.47) | PLGPLAUF10KLKB1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |